Detection of a novel HLA-A allele by polymerase chain reaction-sequence-specific oligonucleotide typing: HLA-A*0252

Tissue Antigens. 2004 Jun;63(6):587-8. doi: 10.1111/j.0001-2815.2004.00207.x.

Abstract

Anew human leukocyte antigen (HLA) class I allele, HLA-A*0252, has been found during routine typing of samples for the Australian Bone Marrow Donor Registry. A*0252 differs from A*020101 at four codon positions, with all the new polymorphisms resulting in an amino acid change. The amino acids involved are located in the antigen-binding region of the HLA protein.

MeSH terms

  • Base Sequence
  • Exons
  • HLA-A Antigens / genetics*
  • HLA-A2 Antigen
  • Humans
  • Molecular Sequence Data
  • Polymerase Chain Reaction

Substances

  • HLA-A Antigens
  • HLA-A*02:52 antigen
  • HLA-A2 Antigen

Associated data

  • GENBANK/AF417237
  • GENBANK/AF417238