New HLA-B alleles detected by polymerase chain reaction-sequence-specific oligonucleotide typing: HLA-B*0725, B*0728, and B*3808

Tissue Antigens. 2004 Jun;63(6):598-9. doi: 10.1111/j.0001-2815.2004.00205.x.

Abstract

Three novel alleles, human leukocyte antigen (HLA)-B*0725, B*0728, and B*3808, were discovered during routine genotyping of samples for the Australian Bone Marrow Donor Registry and Australian Cord Blood Bank. The new alleles contain amino acid changes in the antigen-binding site of the expressed HLA protein, which may alter the antigen-binding properties of the functional protein.

MeSH terms

  • Base Sequence
  • HLA-B Antigens / genetics*
  • HLA-B38 Antigen
  • HLA-B7 Antigen
  • Humans
  • Molecular Sequence Data
  • Polymerase Chain Reaction

Substances

  • HLA-B Antigens
  • HLA-B*07 antigen
  • HLA-B*07:25 antigen
  • HLA-B*07:28 antigen
  • HLA-B*38:08 antigen
  • HLA-B38 Antigen
  • HLA-B7 Antigen

Associated data

  • GENBANK/AF313415
  • GENBANK/AF313416
  • GENBANK/AF402320
  • GENBANK/AF402321
  • GENBANK/AF402322
  • GENBANK/AF402323