Arterio-embolic ischemic stroke in children with moyamoya disease

Childs Nerv Syst. 2005 Feb;21(2):104-7. doi: 10.1007/s00381-004-0962-y. Epub 2004 May 18.

Abstract

Introduction: Moyamoya (MM) disease is a rare steno-occlusive cerebrovascular disease known to occur in children and adults. The most serious complications in children are developmental delay and mental retardation due to recurrent hemodynamic stroke.

Cases: We report two pediatric patients without coagulopathy who suffered from severe arterio-embolic ischemic complications despite antiplatelet medication.

Discussion: These observations underline the potential impact of cerebral thromboembolism on the pathophysiology of the stroke and thus on the treatment of children with MM disease.

Publication types

  • Case Reports

MeSH terms

  • Anterior Cerebral Artery / pathology*
  • Anterior Cerebral Artery / physiopathology
  • Cerebral Angiography / methods
  • Child
  • Diffusion Magnetic Resonance Imaging / methods
  • Humans
  • Male
  • Moyamoya Disease / complications*
  • Moyamoya Disease / drug therapy
  • Moyamoya Disease / pathology*
  • Stroke / etiology*
  • Stroke / pathology