Evaluation of a cumulative prognostic score based on the systemic inflammatory response in patients undergoing potentially curative surgery for colorectal cancer

K Canna; D C McMillan; R F McKee; A-M McNicol; P G Horgan; C S McArdle

doi:10.1038/sj.bjc.6601757

Evaluation of a cumulative prognostic score based on the systemic inflammatory response in patients undergoing potentially curative surgery for colorectal cancer

Br J Cancer. 2004 May 4;90(9):1707-9. doi: 10.1038/sj.bjc.6601757.

Authors

K Canna¹, D C McMillan, R F McKee, A-M McNicol, P G Horgan, C S McArdle

Affiliation

¹ University Department of Surgery, Glasgow Royal Infirmary, Alexandra Parade, Glasgow G31 2ER, Scotland, UK.

Abstract

The value of combining Dukes' stage and C-reactive protein to form a cumulative prognostic score was assessed in 147 patients undergoing potentially curative resection for colorectal cancer. The cancer-specific survival rates at 3 years for patients with a cumulative prognostic score of 0, 1 and 2 were 100, 77 and 40%, respectively (HR 4.76, 2.78-8.15, P<0.001).

Publication types

Comparative Study

MeSH terms

Adult
Aged
Biomarkers, Tumor / analysis*
C-Reactive Protein / analysis*
Colorectal Neoplasms / mortality*
Colorectal Neoplasms / surgery*
Female
Humans
Inflammation
Male
Middle Aged
Neoplasm Staging
Prognosis
Survival Analysis
Treatment Outcome

Substances

Biomarkers, Tumor
C-Reactive Protein