Abstract
The pharmacokinetics of the new triamilide antibiotic tulathromycin was investigated in two cattle studies. Following a single subcutaneous injection, the drug was rapidly absorbed and bioavailability was excellent. High and persistent levels of the drug in lung tissue were observed as well. These attributes are advantageous for an antimicrobial drug indicated for the treatment of bacterial and mycoplasmal respiratory diseases in cattle.
Publication types
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Clinical Trial
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Randomized Controlled Trial
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Anti-Infective Agents / administration & dosage
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Anti-Infective Agents / blood
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Anti-Infective Agents / pharmacokinetics*
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Area Under Curve
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Cattle / metabolism*
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Disaccharides / administration & dosage
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Disaccharides / blood
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Disaccharides / pharmacokinetics*
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Female
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Heterocyclic Compounds / administration & dosage
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Heterocyclic Compounds / blood
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Heterocyclic Compounds / pharmacokinetics*
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Injections, Intravenous / veterinary
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Injections, Subcutaneous / veterinary
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Lung / metabolism*
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Male
Substances
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Anti-Infective Agents
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Disaccharides
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Heterocyclic Compounds
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tulathromycin