Biomedicine. Parkinson's--divergent causes, convergent mechanisms

Science. 2004 May 21;304(5674):1120-2. doi: 10.1126/science.1098966.
No abstract available

Publication types

  • Comment

MeSH terms

  • Animals
  • Brain / metabolism
  • Dopamine / metabolism
  • Electron Transport Complex I / metabolism
  • Humans
  • Intracellular Signaling Peptides and Proteins
  • Mitochondria / enzymology
  • Mitochondria / metabolism*
  • Mutation
  • Nerve Tissue Proteins / genetics
  • Nerve Tissue Proteins / metabolism
  • Neurons / metabolism
  • Oncogene Proteins / genetics
  • Oncogene Proteins / metabolism
  • Oxidative Stress
  • Parkinson Disease / etiology*
  • Parkinson Disease / genetics*
  • Parkinson Disease / metabolism
  • Phosphorylation
  • Protein Deglycase DJ-1
  • Protein Kinases / genetics*
  • Protein Kinases / metabolism*
  • Reactive Oxygen Species / metabolism
  • Synucleins
  • Ubiquitin Thiolesterase / genetics
  • Ubiquitin Thiolesterase / metabolism
  • Ubiquitin-Protein Ligases / genetics
  • Ubiquitin-Protein Ligases / metabolism

Substances

  • Intracellular Signaling Peptides and Proteins
  • Nerve Tissue Proteins
  • Oncogene Proteins
  • Reactive Oxygen Species
  • Synucleins
  • Ubiquitin-Protein Ligases
  • parkin protein
  • Protein Kinases
  • PTEN-induced putative kinase
  • PARK7 protein, human
  • Protein Deglycase DJ-1
  • Ubiquitin Thiolesterase
  • Electron Transport Complex I
  • Dopamine