[Experiment study on biological and immunological characteristics of modified DNL of oral squamous cell carcinoma with TNF-alpha gene]

Shanghai Kou Qiang Yi Xue. 1996 Mar;5(1):13-6.
[Article in Chinese]

Abstract

Growing characteristic of gene-transduced and nontransduced DNL in medium of containing rIL-2 was compared,and growing characteristic of gene-transduced DNL in medium of non containing rIL-2 was analyzed.DNA index (DI),cell cycle and immunologic phenotypes of gene-transduced and nontransduced DNL were analyzed with FACS.The results revealed interfered with growth,DL,cell cycle and immunologic phenotypes of DNL,and gene-transduced DNL couldn't growing infinitely.