Abstract
Two new 18(13-->12)-abeo-lanostane triterpenoid acids, ananosic acids B (1) and C (2), were isolated from the stems of Kadsura anaosma. Their structures were elucidated by spectral studies and chemical transformation. Compounds 1 and 2 were evaluated for cytotoxicity using CCRF-CEM leukemia cells and HeLa cells.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Antineoplastic Agents, Phytogenic / chemistry
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Antineoplastic Agents, Phytogenic / isolation & purification*
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Antineoplastic Agents, Phytogenic / pharmacology
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Drug Screening Assays, Antitumor
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Drugs, Chinese Herbal / chemistry
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Drugs, Chinese Herbal / isolation & purification*
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Drugs, Chinese Herbal / pharmacology
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HeLa Cells
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Humans
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Inhibitory Concentration 50
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Kadsura / chemistry*
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Lanosterol / analogs & derivatives
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Lanosterol / chemistry
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Lanosterol / isolation & purification*
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Lanosterol / pharmacology
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Molecular Structure
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Nuclear Magnetic Resonance, Biomolecular
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Plant Stems / chemistry
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Plants, Medicinal / chemistry*
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Triterpenes / chemistry
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Triterpenes / isolation & purification*
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Triterpenes / pharmacology
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Tumor Cells, Cultured
Substances
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Antineoplastic Agents, Phytogenic
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Drugs, Chinese Herbal
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Triterpenes
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ananosic acid B
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ananosic acid C
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Lanosterol