Acute pseudobulbar palsy as the initial presentation of intravascular lymphomatosis

Adrià Arboix; Imgard Costa; Carles Besses; Jordi Sans-Sabrafen

doi:10.1016/j.ejim.2004.01.015

Acute pseudobulbar palsy as the initial presentation of intravascular lymphomatosis

Eur J Intern Med. 2004 Apr;15(2):128-130. doi: 10.1016/j.ejim.2004.01.015.

Authors

Adrià Arboix¹, Imgard Costa, Carles Besses, Jordi Sans-Sabrafen

Affiliation

¹ Acute Stroke Unit, Department of Neurology, Hospital del Sagrat Cor, Viladomat 288, E-08029 Barcelona, Spain.

PMID: 15172029
DOI: 10.1016/j.ejim.2004.01.015

Abstract

We describe the case of a 76-year-old male patient who developed acute manifestations of pseudobulbar palsy without a history of stroke or vascular risk factors as the first manifestation of intravascular lymphomatosis. Neurological symptoms of acute pseudobulbar palsy appeared on the second postoperative day after transurethral prostatectomy for the treatment of prostatic hypertrophy. Intravascular lymphomatosis was diagnosed from microscopic findings and immunohistochemical staining of the surgical specimen. Chemotherapy was started, but the patient died due to sepsis secondary to bone marrow aplasia. Intravascular lymphomatosis should be considered a rare potential cause of acute pseudobulbar palsy.