Abstract
The type strain of Pseudomonas aeruginosa, PAO1, showed great upregulation of many nitrosative defense genes upon treatment with S-nitrosoglutathione, while the mucoid strain PAO578II showed no further upregulation above its constitutive upregulation of nor and fhp. NO* consumption however, showed that both strains mount functional, protein synthesis-dependent NO*-consumptive responses.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Bacterial Proteins / genetics
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Bacterial Proteins / metabolism*
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Gene Expression Profiling
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Heat-Shock Response*
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Humans
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Nitric Oxide / metabolism
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Oligonucleotide Array Sequence Analysis / methods*
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Pseudomonas aeruginosa / genetics
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Pseudomonas aeruginosa / growth & development*
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Pseudomonas aeruginosa / physiology*
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S-Nitrosoglutathione / pharmacology*
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Up-Regulation
Substances
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Bacterial Proteins
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Nitric Oxide
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S-Nitrosoglutathione