Lipids of the zygomycete Absidia corymbifera F-965

Phytochemistry. 2004 May;65(9):1239-46. doi: 10.1016/j.phytochem.2004.04.004.

Abstract

The cell lipids of the zygomycete Absidia corymbifera F-965 extracted with isopropanol and CHCl3-MeOH mixtures at the exponential growth phase comprise 20+/-2% of mycelium dry wt. The lipids consist of: triacylglycerols (51% of the total lipids extracted), diacylglycerols (9%), monoacylglycerols (3%), ergosterol (5%), ergosterol peroxide (5alpha,8alpha-epidioxyergosta-6,22-diene-3beta-ol) (3%), fatty-acid esters of ergosterol (less than 0.5%), free fatty acids (4%), glucocerebroside (3%), and glycerophospholipids (22%). The main phospholipids are phosphatidylethanolamine (39% of the total phospholipids), phosphatidyl-myo-inositol (17%), diphosphatidylglycerol (12%), phosphatidic acid (7%), phosphatidylcholine (6%), phosphatidylglycerol (3%), and two unusual phospholipids reported earlier, N-acetylphosphatidylethanolamine (7%) and N-ethoxycarbonyl phosphatidylethanolamine (9%). In addition, two unknown acidic phospholipids are present in traces. Saturated fatty acids of the lipids are dominated by n-hexadecanoic acid and unsaturated ones by octadecenoic acid; octadecadienoic and octadecatrienoic acids are present in lesser amounts. Ergosterol peroxide as well as the above glucocerebroside which contains 9-methylsphinga-4(E),9(E)-dienine have first been revealed in zygomycetes.

MeSH terms

  • Absidia / chemistry*
  • Absidia / genetics
  • Chromatography, Gas
  • Ergosterol / analogs & derivatives*
  • Ergosterol / chemistry
  • Ergosterol / isolation & purification
  • Fatty Acids / analysis
  • Fatty Acids / chemistry
  • Glucosylceramides / chemistry
  • Glucosylceramides / isolation & purification
  • Lipids / chemistry*
  • Lipids / isolation & purification
  • Molecular Structure
  • Phospholipids / chemistry
  • Phospholipids / isolation & purification

Substances

  • Fatty Acids
  • Glucosylceramides
  • Lipids
  • Phospholipids
  • ergosterol-5,8-peroxide
  • Ergosterol