Abstract
Persistent drug-induced movement disorders (tardive syndromes) remain an important clinical problem and consist of a variety of involuntary movements appearing in a patient exposed to a dopamine-blocking agent. The current state of knowledge on this topic is summarised in this article. Clinical aspects (tardive dyskinesia, tardive dystonia and other forms), prevalence, risk factors, prevention and management are discussed.
MeSH terms
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Akathisia, Drug-Induced / physiopathology
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Dopamine Antagonists / adverse effects*
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Dyskinesia, Drug-Induced / physiopathology*
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Dyskinesia, Drug-Induced / therapy
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Dystonia / chemically induced
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Dystonia / physiopathology
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Humans
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Myoclonus / chemically induced
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Receptors, Dopamine / drug effects
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Serotonin / physiology
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Tics / chemically induced
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Tremor / chemically induced
Substances
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Dopamine Antagonists
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Receptors, Dopamine
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Serotonin