Abstract
In view of biological activities of azole nucleosides and apio-dideoxynucleoside, novel apio nucleoside analogues (1 and 2) with thiazole and triazole base moiety were synthesized using 2,3-O-isopropylidene-apio-beta-D-furanose (3), which was prepared from D-mannose.
MeSH terms
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Mannose / analogs & derivatives*
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Mannose / chemistry
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Nucleosides / chemical synthesis*
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Nucleosides / chemistry
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Structure-Activity Relationship
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Thiazoles / chemical synthesis*
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Thiazoles / chemistry
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Triazoles / chemical synthesis*
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Triazoles / chemistry
Substances
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Nucleosides
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Thiazoles
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Triazoles
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Mannose