Lymphatic vasculature: development, molecular regulation and role in tumor metastasis and inflammation

Trends Immunol. 2004 Jul;25(7):387-95. doi: 10.1016/j.it.2004.05.003.

Authors

Pipsa Saharinen¹, Tuomas Tammela, Marika J Karkkainen, Kari Alitalo

Affiliation

¹ Molecular/Cancer Biology Laboratory and Ludwig Institute for Cancer Research, Biomedicum Helsinki and Helsinki University Central Hospital, University of Helsinki, P.O.B. 63 (Haartmaninkatu 8), 00014 Helsinki, Finland.

PMID: 15207507
DOI: 10.1016/j.it.2004.05.003

No abstract available

Publication types

Review

MeSH terms

Animals
Endothelial Cells / physiology
Homeodomain Proteins / physiology
Humans
Inflammation / metabolism
Inflammation / physiopathology*
Lymphangiogenesis / physiology*
Lymphatic Vessels / embryology
Lymphatic Vessels / physiology*
Lymphedema / physiopathology
Neoplasm Metastasis / physiopathology*
Receptors, Vascular Endothelial Growth Factor / physiology
Tumor Suppressor Proteins
Vascular Endothelial Growth Factor C / physiology
Vascular Endothelial Growth Factor D / physiology
Vascular Endothelial Growth Factor Receptor-3 / physiology

Substances

Homeodomain Proteins
Tumor Suppressor Proteins
Vascular Endothelial Growth Factor C
Vascular Endothelial Growth Factor D
prospero-related homeobox 1 protein
Receptors, Vascular Endothelial Growth Factor
Vascular Endothelial Growth Factor Receptor-3