Effects of bupivacaine enantiomers and ropivacaine on vasorelaxation mediated by adenosine triphosphate-sensitive K(+) channels in the rat aorta

Anesthesiology. 2004 Jul;101(1):251-4. doi: 10.1097/00000542-200407000-00040.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amides / chemistry
  • Amides / pharmacology*
  • Anesthetics, Local / chemistry
  • Anesthetics, Local / pharmacology*
  • Animals
  • Aorta, Thoracic / drug effects*
  • Bupivacaine / chemistry
  • Bupivacaine / pharmacology*
  • Cromakalim / pharmacology
  • Dose-Response Relationship, Drug
  • Endothelium, Vascular / physiology
  • In Vitro Techniques
  • Male
  • Membrane Proteins / drug effects*
  • Muscle, Smooth, Vascular / drug effects*
  • Papaverine / pharmacology
  • Potassium Channels
  • Rats
  • Rats, Wistar
  • Ropivacaine
  • Stereoisomerism
  • Vasodilation / drug effects*
  • Vasodilator Agents / pharmacology

Substances

  • Amides
  • Anesthetics, Local
  • Membrane Proteins
  • Potassium Channels
  • Vasodilator Agents
  • mitochondrial K(ATP) channel
  • Cromakalim
  • Ropivacaine
  • Papaverine
  • Bupivacaine