Chirality induction on achiral N-methyl aromatic amide oligomers bearing terminal carboxy groups with chiral amines

Tatsuya Nishimura; Katsuhiro Maeda; Eiji Yashima

doi:10.1002/chir.20028

Chirality induction on achiral N-methyl aromatic amide oligomers bearing terminal carboxy groups with chiral amines

Chirality. 2004:16 Suppl:S12-22. doi: 10.1002/chir.20028.

Authors

Tatsuya Nishimura¹, Katsuhiro Maeda, Eiji Yashima

Affiliation

¹ Department of Molecular Design and Engineering, Graduate School of Engineering, Nagoya University, Chikusa-ku, Nagoya, Japan.

PMID: 15239068
DOI: 10.1002/chir.20028

Abstract

Novel unsymmetrical N-methyl aromatic amide oligomers bearing two carboxy groups at both ends were synthesized and their complexation with various optically active amines in solution was investigated using circular dichroism (CD) spectroscopy. The complexes showed a characteristic induced CD in the absorption region due to the aromatic amide reflecting the absolute configuration of the chiral amines.