Abstract
Objective:
To summarize our experience in the diagnosis and treatment of malignant pancreatic endocrine tumour.
Methods:
We retrospectively reviewed 36 cases of malignant pancreatic endocrine tumours in our hospital from July 1987 to April 2002, and summarized its clinical features.
Results:
Liver metastasis was the main malignant manifestation of malignant pancreatic endocrine tumours (incidence rate 72.2%). Removals of primary lesion and isolated hepatic metastatic lesion were means of curative therapy. Interventional chemotherapy was an important adjuvant treatment.
Conclusion:
Comprehensive therapy plays an important role in improving the prognosis of malignant pancreatic endocrine tumour.
MeSH terms
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Adult
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Aged
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Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
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Carcinoma, Islet Cell / diagnosis
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Carcinoma, Islet Cell / pathology
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Carcinoma, Islet Cell / therapy
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Chemotherapy, Adjuvant
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Female
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Follow-Up Studies
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Gastrectomy
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Gastrinoma / diagnosis
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Gastrinoma / pathology
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Gastrinoma / therapy
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Glucagonoma / diagnosis
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Glucagonoma / pathology
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Glucagonoma / therapy
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Humans
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Insulinoma / diagnosis
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Insulinoma / pathology
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Insulinoma / therapy
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Liver Neoplasms / secondary*
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Liver Neoplasms / therapy
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Lymphatic Metastasis
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Male
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Middle Aged
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Neoplasm Invasiveness
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Pancreas / surgery*
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Pancreatectomy
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Pancreatic Neoplasms / diagnosis*
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Pancreatic Neoplasms / pathology
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Pancreatic Neoplasms / therapy*
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Retrospective Studies