PAF, eosinophils and asthma

J Lipid Mediat. 1992 Jun-Jul;5(2):155-8.

Abstract

PAF has many inflammatory effects in the airways and closely mimics the pathophysiology of asthma. PAF is a potent stimulus to eosinophil accumulation and activation and may be involved in the eosinophilic inflammation which characterises asthma and airway hyperresponsiveness.

MeSH terms

  • Asthma / pathology*
  • Eosinophils / cytology*
  • Eosinophils / immunology
  • Humans
  • Inflammation / pathology
  • Platelet Activating Factor / physiology*

Substances

  • Platelet Activating Factor