Abstract
A new 4-(N,N-dimethylamino) phthalimide-based environment-sensitive fluorescent building block for solid phase peptide synthesis, has been synthesized and incorporated into peptides. Peptides incorporating this residue show great potential for biological applications in sensing protein/protein interactions.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Amino Acids / chemistry*
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Fluorenes / chemistry*
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Fluorescent Dyes / chemistry*
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Molecular Structure
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Peptides / chemical synthesis*
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Peptides / chemistry
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Phthalimides / chemical synthesis
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Phthalimides / chemistry
Substances
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4-(N,N-dimethylamino) phthalimide
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Amino Acids
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Fluorenes
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Fluorescent Dyes
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N(alpha)-fluorenylmethyloxycarbonylamino acids
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Peptides
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Phthalimides