Callynormine A, a new marine cyclic peptide of a novel class

Org Lett. 2004 Jul 22;6(15):2543-5. doi: 10.1021/ol0491787.

Abstract

[structure: see text] A novel cyclic peptide, callynormine A, was isolated from the Kenyan marine sponge Callyspongia abnormis and its structure elucidated by interpretation of its NMR data and X-ray diffraction analysis. Callynormine A represents a new class of heterodetic cyclic peptides (designated endiamino peptides) possessing an alpha-amido-beta-aminoacrylamide cyclization functionality.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Callyspongia / chemistry*
  • Crystallography, X-Ray
  • Cyclization
  • Kenya
  • Molecular Structure
  • Nuclear Magnetic Resonance, Biomolecular
  • Peptides, Cyclic / chemistry
  • Peptides, Cyclic / classification
  • Peptides, Cyclic / isolation & purification*
  • Stereoisomerism

Substances

  • Peptides, Cyclic
  • callynormine A