Abstract
We extend the generality of nucleic acid-based structural nanotechnology by incorporating non-natural nucleic acids into a DNA double crossover (DX) molecule; visualizing two-dimensional arrays of these DX molecules by Atomic Force Microscopy (AFM) enables us to measure the helical repeat of any heteroduplex sequence capable of forming the outer arms of a DX.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, U.S. Gov't, Non-P.H.S.
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Base Sequence
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Biomimetic Materials / chemical synthesis
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Biomimetic Materials / chemistry*
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DNA / chemical synthesis
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DNA / chemistry*
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Microscopy, Atomic Force
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Molecular Conformation
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Molecular Sequence Data
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Nanotechnology / methods
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Peptide Nucleic Acids / chemistry*
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Polymers / chemistry*
Substances
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Peptide Nucleic Acids
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Polymers
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DNA