Stereoselective synthesis of 3-alkylideneoxindoles using tandem In-mediated carbometalation and Pd-catalyzed cross-coupling reaction

Reiko Yanada; Shingo Obika; Munetaka Oyama; Yoshiji Takemoto

doi:10.1021/ol048866n

Stereoselective synthesis of 3-alkylideneoxindoles using tandem In-mediated carbometalation and Pd-catalyzed cross-coupling reaction

Org Lett. 2004 Aug 5;6(16):2825-8. doi: 10.1021/ol048866n.

Authors

Reiko Yanada¹, Shingo Obika, Munetaka Oyama, Yoshiji Takemoto

Affiliation

¹ Graduate School of Pharmaceutical Sciences, Kyoto University, Yoshida, Sakyo-ku, Kyoto 606-8501, Japan.

PMID: 15281779
DOI: 10.1021/ol048866n

Abstract

Efficient methods for stereoselective synthesis of various (E)-, (Z)-, and disubstituted 3-alkylideneoxindoles were investigated using tandem In-mediated carbometalation and ligandless Pd-catalyzed coupling reaction.