In this work, handedness differences in the widths of right and left craniofacial regions were studied in a healthy sample of 39 male and 43 female students, 17 to 23 years old. Width of craniofacial regions was assessed by computerized tomography. Handedness was associated with the left face width especially for women. The left facial region was larger for right-handers than left-handers. The smaller measure for the left face of left-handers might be associated with an advantage of left ear sensitivity.