V-antigen genotype and phenotype analyses of clinical isolates of Pseudomonas aeruginosa

J Clin Microbiol. 2004 Aug;42(8):3857-60. doi: 10.1128/JCM.42.8.3857-3860.2004.

Abstract

The pcrV genotype was analyzed in clinical isolates of Pseudomonas aeruginosa which showed a negative phenotype for secretion of V-antigen PcrV. The suppression of PcrV secretion in these isolates was due not to a lack of the pcrV gene but rather to suppression of PcrV expression.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Aged
  • Antigens, Bacterial / genetics*
  • Bacterial Toxins / genetics*
  • Base Sequence
  • Child
  • Child, Preschool
  • Cystic Fibrosis / microbiology
  • DNA Primers
  • DNA, Bacterial / genetics
  • Humans
  • Middle Aged
  • Phenotype
  • Pore Forming Cytotoxic Proteins
  • Pseudomonas Infections / diagnosis*
  • Pseudomonas aeruginosa / genetics*
  • Pseudomonas aeruginosa / immunology
  • Pseudomonas aeruginosa / isolation & purification*

Substances

  • Antigens, Bacterial
  • Bacterial Toxins
  • DNA Primers
  • DNA, Bacterial
  • Pore Forming Cytotoxic Proteins
  • antigen V, Pseudomonas