Persistent nonfused segments of the basilar artery: longitudinal versus axial nonfusion

AJNR Am J Neuroradiol. 2004 Aug;25(7):1194-6.

Abstract

Embryologic development of the basilar artery occurs along two axis systems: longitudinal fusion and axial fusion. Longitudinal fusion consists of midline fusion of paired ventral arteries and reflects the simplified pattern of arterial anatomy found in the spinal cord. Axial fusion consists of fusion of the distal basilar artery, which arises from the caudal division of the internal carotid artery, to the midbasilar agenesis to the posterior inferior cerebellar artery termination of the vertebral arteries. Persistent longitudinal nonfusion (or complete duplication) of the basilar artery is very rare, and persistent axial nonfusion is even rarer. We report one case of persistent longitudinal nonfusion of the basilar artery in a 3-year-old boy and a case of persistent axial nonfusion of the basilar artery in a 43-year-old man.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Angiography, Digital Subtraction*
  • Anticonvulsants / therapeutic use
  • Basilar Artery / abnormalities*
  • Basilar Artery / embryology
  • Basilar Artery / pathology
  • Cerebellum / blood supply
  • Cerebral Angiography*
  • Child, Preschool
  • Diagnosis, Differential
  • Drug Therapy, Combination
  • Epilepsy, Tonic-Clonic / congenital*
  • Epilepsy, Tonic-Clonic / diagnosis
  • Epilepsy, Tonic-Clonic / drug therapy
  • Humans
  • Image Processing, Computer-Assisted*
  • Magnetic Resonance Angiography*
  • Magnetic Resonance Imaging*
  • Male
  • Phenobarbital / therapeutic use
  • Sensitivity and Specificity
  • Vertebral Artery / abnormalities
  • Vertebral Artery / pathology
  • Vertebrobasilar Insufficiency / congenital*
  • Vertebrobasilar Insufficiency / diagnosis

Substances

  • Anticonvulsants
  • Phenobarbital