It is reasonable to speculate that migrainous infarction may develop in different territories of cerebral arteries. However, this condition was rarely reported before. Here we described two patients (one woman, 29 year-old; one man, 47 year-old) with a history of migraine with aura, had ischemic strokes during the migraine attack. The ischemic stroke of the female patient involved the territories of the posterior cerebral and anterior choroidal arteries; whereas the male patient had two episodes of ischemic strokes, involving the territories of the middle and posterior cerebral arteries sequentially. Both patients recovered well during the follow-up periods. We suggest that migrainous infarction can involve different arterial territories.