Blocking the L-type Ca2+ channel with a gem: a paradigm for a more specific Ca2+ channel blocker

Circ Res. 2004 Aug 20;95(4):337-9. doi: 10.1161/01.RES.0000141018.33292.21.
No abstract available

Publication types

  • Comment
  • Editorial

MeSH terms

  • Adenoviridae / genetics
  • Animals
  • Atrial Fibrillation / physiopathology
  • Atrial Fibrillation / therapy
  • Calcium Channel Blockers / pharmacology*
  • Calcium Channels, L-Type / drug effects*
  • Calcium Channels, L-Type / genetics
  • Drug Design
  • Genetic Therapy
  • Genetic Vectors / pharmacology
  • Guanosine Triphosphate / physiology
  • Guinea Pigs
  • Heart Conduction System / drug effects
  • Heart Conduction System / metabolism
  • Immediate-Early Proteins / genetics
  • Immediate-Early Proteins / physiology*
  • Ion Channel Gating / drug effects
  • Models, Biological
  • Monomeric GTP-Binding Proteins / genetics
  • Monomeric GTP-Binding Proteins / physiology*
  • Multigene Family
  • Protein Subunits
  • Protein Transport
  • Recombinant Fusion Proteins / physiology
  • Sus scrofa

Substances

  • Calcium Channel Blockers
  • Calcium Channels, L-Type
  • Immediate-Early Proteins
  • Protein Subunits
  • Recombinant Fusion Proteins
  • Guanosine Triphosphate
  • Gem protein, mouse
  • Monomeric GTP-Binding Proteins