Abstract
This clinical pilot study was a randomized, controlled, open-label study in 80 patients with acute myocardial infarction and was designed to examine the effects of a novel free radical scavenger, edaravone. Administration of edaravone before myocardial reperfusion was associated with smaller enzymatic infarcts and better clinical outcome.
Publication types
-
Clinical Trial
-
Randomized Controlled Trial
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Aged
-
Angioplasty, Balloon, Coronary*
-
Antipyrine / adverse effects
-
Antipyrine / analogs & derivatives*
-
Antipyrine / therapeutic use*
-
Creatine Kinase / blood
-
Creatine Kinase, MB Form
-
Edaravone
-
Female
-
Free Radical Scavengers / adverse effects
-
Free Radical Scavengers / therapeutic use*
-
Humans
-
Isoenzymes / blood
-
Male
-
Middle Aged
-
Myocardial Infarction / diagnosis
-
Myocardial Infarction / drug therapy*
-
Myocardial Reperfusion Injury / diagnosis
-
Myocardial Reperfusion Injury / prevention & control*
-
Pilot Projects
-
Stents*
-
Thrombolytic Therapy*
-
Treatment Outcome
Substances
-
Free Radical Scavengers
-
Isoenzymes
-
Creatine Kinase
-
Creatine Kinase, MB Form
-
Edaravone
-
Antipyrine