Abstract
Colorectal MSI tumors are associated with an increased immune response. On the other hand, immunodeficient patients are more prone to lymphomas with the MSI phenotype. These facts are of wide interest in understanding the complex link between immunity and cancer, particularly of the MSI phenotype. Specific attention to the host immune system should thus be considered in the treatment of patients with MSI tumors.
MeSH terms
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Acquired Immunodeficiency Syndrome / complications*
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Acquired Immunodeficiency Syndrome / genetics
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Acquired Immunodeficiency Syndrome / immunology
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Animals
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Antigens, Neoplasm / genetics
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Antigens, Neoplasm / immunology
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Carcinoma / genetics
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Carcinoma / immunology
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Cell Transformation, Neoplastic / genetics
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Cell Transformation, Neoplastic / immunology*
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Chromosomal Instability / genetics*
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Colorectal Neoplasms / genetics
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Colorectal Neoplasms / immunology
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Humans
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Lymphocyte Activation / genetics
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Lymphocyte Activation / immunology
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Microsatellite Repeats / genetics*
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Neoplasms / genetics
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Neoplasms / immunology*