Abstract
A study of 257 French invasive pneumococci isolated between 2000 and 2002 showed high rates of nonsusceptibility to penicillin and macrolides (50%), contrasting with a low frequency of resistance to amoxicillin or levofloxacin (<1%) and tolerance to vancomycin (0%). The genetic homogeneity of some serogroups, including serogroup 1, enhanced the risk of epidemiological changes.
MeSH terms
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Adult
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Amoxicillin / pharmacology
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Child
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Drug Resistance, Bacterial
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Electrophoresis, Gel, Pulsed-Field
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France / epidemiology
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Humans
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Microbial Sensitivity Tests
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Molecular Epidemiology
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Penicillin Resistance
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Pneumococcal Infections / epidemiology*
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Pneumococcal Infections / microbiology*
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Population Surveillance
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Serotyping
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Streptococcus pneumoniae / drug effects*
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Streptococcus pneumoniae / genetics*