Approach to geminally alkylated azaphthalans via a consecutive double desilylation-alkylation reaction: application to a synthesis of cerpegin

Tarun K Sarkar; Sankar Basak

doi:10.1021/ol0489797

Approach to geminally alkylated azaphthalans via a consecutive double desilylation-alkylation reaction: application to a synthesis of cerpegin

Org Lett. 2004 Aug 19;6(17):2925-7. doi: 10.1021/ol0489797.

Authors

Tarun K Sarkar¹, Sankar Basak

Affiliation

¹ Department of Chemistry, Indian Institute of Technology, Kharagpur, 721302, India. [email protected]

PMID: 15330649
DOI: 10.1021/ol0489797

Abstract

A new approach to geminally alkylated azaphthalans and an application of this chemistry to the synthesis of the pyridone alkaloid, cerpegin, is reported.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Alkaloids / chemical synthesis*
Alkylation
Crystallography, X-Ray
Molecular Structure
Nuclear Magnetic Resonance, Biomolecular
Pyridones / chemical synthesis*

Substances

Alkaloids
Pyridones
cerpegin