New potent and selective A1 adenosine receptor agonists

Bioorg Med Chem. 2004 Sep 15;12(18):4877-84. doi: 10.1016/j.bmc.2004.07.004.

Abstract

Thiirane analogs of ENAdo have been synthesised and found to be extremely potent and selective A(1) adenosine receptor agonists.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adenosine A1 Receptor Agonists*
  • Animals
  • Cricetinae
  • Humans
  • PC12 Cells
  • Rats
  • Sulfides / chemistry*
  • Sulfides / pharmacology*

Substances

  • Adenosine A1 Receptor Agonists
  • Sulfides
  • ethylene sulfide