Cognitive decline in high-functioning older persons is associated with an increased risk of hospitalization

J Am Geriatr Soc. 2004 Sep;52(9):1456-62. doi: 10.1111/j.1532-5415.2004.52407.x.

Abstract

Objectives: To examine hospital use for patients with evidence of cognitive decline indicative of early cognitive impairment.

Design: Medicare Part A hospital utilization data were linked to data from the MacArthur Research Network on Successful Aging Community Study to examine the association between baseline cognition and decline in cognitive function over a 3-year period and any hospitalization over that same period.

Setting: New Haven, Connecticut, and East Boston, Massachusetts.

Participants: Subjects (N=598) were from two sites of the MacArthur Research Network on Successful Aging Community Study, a 7-year cohort study of community-dwelling older persons with high physical and cognitive functioning.

Measurements: Multivariate logistic regression was used to determine the association between any hospitalization over 3 years (1988-91) as the outcome variable and baseline cognitive function and decline in cognition over 3 years as primary predictor variables. Decline was based upon repeated (1988 and 1991) measures of delayed verbal recall and the Short Portable Mental Status Questionnaire (SPMSQ).

Results: Of 598 subjects, 48 died between 1988 and 1991. No baseline (1988) delayed recall scores or change in recall scores (1988-91) were associated with hospitalization. Although 48.2% declined on verbal memory scores, decline was not associated with risk of hospitalization. Of 494 subjects with complete 3-year data, 31.2% declined at least one point on the SPMSQ, and 4.7% declined more than two points. Among individuals aged 75 and older at baseline, the adjusted odds ratio for hospitalization for those who declined more than 2 points compared with those who declined less was 7.8 (95% confidence interval=2.0-30.8).

Conclusion: Although specific memory tests were not associated with hospitalization, high-functioning older persons who experienced decline in overall cognitive function were more likely to be hospitalized. Variation in baseline cognitive function in this high-functioning cohort did not affect hospitalization, but additional research is needed to evaluate associations with other healthcare costs.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Activities of Daily Living
  • Aged
  • Boston / epidemiology
  • Cognition Disorders / complications*
  • Cognition Disorders / diagnosis
  • Cognition Disorders / epidemiology
  • Comorbidity
  • Connecticut / epidemiology
  • Disease Progression
  • Female
  • Geriatric Assessment
  • Hospitalization / statistics & numerical data*
  • Humans
  • Insurance Claim Reporting / statistics & numerical data
  • Logistic Models
  • Longitudinal Studies
  • Male
  • Medicare Part A / statistics & numerical data
  • Memory Disorders / diagnosis
  • Memory Disorders / etiology
  • Multivariate Analysis
  • Neuropsychological Tests
  • Odds Ratio
  • Predictive Value of Tests
  • Psychiatric Status Rating Scales
  • Risk Factors
  • Time Factors