[Intra-alveolar hemorrhages in systemic diseases]

Presse Med. 1992 May 16;21(18):839-42.
[Article in French]

Abstract

Alveolar haemorrhage is usually, but often belatedly, diagnosed in patients presenting with haemoptysis and radiological alveolar syndrome. Its occurrence frequently marks a turn for the worst in the course of a systemic disease, since its prognosis is sombre. Recognizing its early signs might enable treatment to be instituted and prognosis to be improved. In the presence of typical alveolar haemorrhage, if high-dose corticosteroid therapy and immunosuppressants do not improve the symptoms within 48 hours plasmapheresis must be started. Alveolar haemorrhage must be considered a vital emergency justifying this therapeutic approach without waiting for the hypothetical diagnosis of the underlying systemic disease.

Publication types

  • English Abstract

MeSH terms

  • Adolescent
  • Adrenal Cortex Hormones / therapeutic use
  • Adult
  • Aged
  • Anti-Glomerular Basement Membrane Disease / complications
  • Connective Tissue Diseases / complications*
  • Female
  • Granulomatosis with Polyangiitis / complications
  • Hemoptysis / diagnosis
  • Hemoptysis / etiology*
  • Hemoptysis / mortality
  • Hemoptysis / therapy
  • Humans
  • Immunosuppressive Agents / therapeutic use
  • Lupus Erythematosus, Systemic / complications
  • Middle Aged
  • Plasma Exchange
  • Prognosis
  • Vasculitis / complications*

Substances

  • Adrenal Cortex Hormones
  • Immunosuppressive Agents