Myxomatous lesions of the maxilla in children: a case series and review of management

Int J Pediatr Otorhinolaryngol. 2004 Oct;68(10):1251-6. doi: 10.1016/j.ijporl.2004.04.022.

Abstract

Objective: A paucity of data exists in the literature regarding the pediatric bony myxoma. Controversy exists regarding both its histopathologic origins and surgical management. The purpose of this study was to report on our experience in managing these patients, including diagnostic work-up, histopathologic findings and an evaluation of surgical treatment outcomes.

Methods: A retrospective review was undertaken of all consecutive cases of pediatric bony myxoma treated between 1988 and 2001. Tumors were analyzed in terms of clinical data, imaging studies, histopathology and surgical treatment. A selective review of the literature regarding management of the bony myxoma is also presented.

Results: Five lesions were identified, all of which occurred in the maxillary bone. Histopathologically our cases did not show a strong association with odontogenic epithelium. All cases were treated by surgical resection with conservative margins. No recurrences were documented over a mean follow-up period of 8.5 years.

Conclusion: The bony myxoma is a rare lesion in the pediatric population, and initial clinical or radiological misdiagnoses are not uncommon. The presupposed odontogenic origin of these tumors may need reassessment. Conservative resection with narrow margins is a safe and effective therapy for myxomas of the pediatric maxilla.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adolescent
  • Biopsy
  • Child
  • Diagnosis, Differential
  • Disease-Free Survival
  • Female
  • Fibroma* / diagnosis
  • Fibroma* / pathology
  • Fibroma* / surgery
  • Humans
  • Immunohistochemistry
  • Infant
  • Male
  • Maxillary Neoplasms* / diagnosis
  • Maxillary Neoplasms* / pathology
  • Maxillary Neoplasms* / surgery
  • Maxillary Sinus Neoplasms / diagnosis
  • Maxillary Sinus Neoplasms / pathology
  • Maxillary Sinus Neoplasms / surgery
  • Myxoma* / diagnosis
  • Myxoma* / pathology
  • Myxoma* / surgery
  • Retrospective Studies
  • Tomography, X-Ray Computed
  • Treatment Outcome