[Infection with Gnathostoma spinigerum as a cause of eosinophilic oesophagitis]

Dtsch Med Wochenschr. 2004 Sep 17;129(38):1973-5. doi: 10.1055/s-2004-831835.
[Article in German]

Abstract

History and admission findings: A 63-year-old man, who had travelled extensively in Asia and had lived in South Africa, presented with increasing dysphagia. Physical examination showed no abnormalities.

Examinations: Upper gastrointestinal endoscopy showed a concentric oesophageal stenosis, 5 cm long, consisting of thickening of the wall without any sign of malignancy or mucocutaneous lesions. The histological examination of this lesion demonstrated infiltrations of eosinophilic cells. Serology was positive for Gnathostoma spinigerum.

Treatment and clinical course: After treatment with albendazole 400 mg per day for 3 weeks the clinical, histological and serological symptoms resolved completely.

Conclusion: In case of any eosinophilia or local infiltrations of eosinophilic cells, parasitic disease have to be considered.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Albendazole / therapeutic use
  • Animals
  • Anthelmintics / therapeutic use
  • Antibodies, Helminth / blood
  • Blotting, Western
  • Diagnosis, Differential
  • Endoscopy, Digestive System
  • Eosinophilia / parasitology*
  • Esophageal Stenosis / parasitology*
  • Esophagitis / parasitology*
  • Gnathostoma / immunology*
  • Humans
  • Male
  • Middle Aged
  • Spirurida Infections / complications*
  • Spirurida Infections / diagnosis
  • Spirurida Infections / drug therapy
  • Travel

Substances

  • Anthelmintics
  • Antibodies, Helminth
  • Albendazole