Abstract
Reversed-phase preparative HPLC of a methanol extract of the rhizomes of Eremostachys glabra yielded three new iridoid glycosides, namely, 6,9-epi-8-O-acetylshanziside methyl ester, 5,9-epi-penstemoside, and 5,9-epi-7,8-didehydropenstemoside. Their structures were elucidated on the basis of spectroscopic data interpretation. The free-radical scavenging activity of these compounds was assessed using the DPPH assay.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Chromatography, High Pressure Liquid
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Free Radical Scavengers / chemistry
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Free Radical Scavengers / isolation & purification*
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Free Radical Scavengers / pharmacology
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Glycosides / chemistry
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Glycosides / isolation & purification*
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Glycosides / pharmacology
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Iran
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Iridoid Glycosides
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Iridoids / chemistry
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Iridoids / isolation & purification*
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Iridoids / pharmacology
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Lamiaceae / chemistry*
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Molecular Structure
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Nuclear Magnetic Resonance, Biomolecular
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Plants, Medicinal / chemistry*
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Rhizome / chemistry
Substances
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5,9-epi-7,8-didehydropenstemoside
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5,9-epi-penstemoside
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6,9-epi-8-O-acetylshanziside methyl ester
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Free Radical Scavengers
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Glycosides
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Iridoid Glycosides
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Iridoids