Renal cell cancer associated with sarcoid-like reaction

Pathol Oncol Res. 2004;10(3):169-71. doi: 10.1007/BF03033747. Epub 2004 Sep 25.

Abstract

An unusual granulomatous reaction within a conventional clear cell renal cancer in a 62 year-old woman is reported. Using immunohistochemical evaluation, cells of the granuloma were CD68 (Kp1), carboxypeptidase M and CD3 positive. No signs of sarcoidosis were found in other organs. According to the few publications that mention cancer associated sarcoid-like reaction, such lesions do not influence the prognosis. Our patient is still well for a 15 months follow-up.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adenocarcinoma, Clear Cell / metabolism
  • Adenocarcinoma, Clear Cell / pathology*
  • Antigens, CD / biosynthesis
  • Antigens, Differentiation, Myelomonocytic / biosynthesis
  • CD3 Complex / biosynthesis
  • Female
  • GPI-Linked Proteins
  • Granuloma / metabolism
  • Granuloma / pathology*
  • Humans
  • Immunohistochemistry
  • Kidney Neoplasms / metabolism
  • Kidney Neoplasms / pathology*
  • Metalloendopeptidases / biosynthesis
  • Middle Aged

Substances

  • Antigens, CD
  • Antigens, Differentiation, Myelomonocytic
  • CD3 Complex
  • CD68 antigen, human
  • GPI-Linked Proteins
  • carboxypeptidase M
  • Metalloendopeptidases