Kayser-Fleischer rings in a patient with basal cell carcinoma: fortuitous diagnosis of presymptomatic Wilson's disease

Mayo Clin Proc. 1992 Feb;67(2):142-3. doi: 10.1016/s0025-6196(12)61315-9.

Abstract

Kayser-Fleischer rings were detected during a routine ophthalmologic workup in a 25-year-old man with basal cell carcinoma of the eyelid. Although the importance of this association is uncertain, the routine preoperative evaluation of basal cell carcinoma led to the presymptomatic diagnosis of Wilson's disease. These disorders are discussed, as are the benefits of a multidisciplinary approach for the diagnosis and management of medical problems.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Alkaline Phosphatase / blood
  • Aspartate Aminotransferases / blood
  • Blood Proteins / chemistry
  • Carcinoma, Basal Cell / complications*
  • Carcinoma, Basal Cell / diagnosis
  • Carcinoma, Basal Cell / surgery
  • Ceruloplasmin / chemistry
  • Copper / administration & dosage
  • Copper / blood
  • Copper / urine
  • Creatinine / blood
  • Diet Therapy
  • Eyelid Neoplasms / complications*
  • Eyelid Neoplasms / diagnosis
  • Eyelid Neoplasms / surgery
  • Hepatolenticular Degeneration / complications
  • Hepatolenticular Degeneration / diagnosis*
  • Hepatolenticular Degeneration / therapy
  • Humans
  • Male
  • Mohs Surgery
  • Ophthalmoscopy
  • Prothrombin Time
  • Trientine / administration & dosage
  • Trientine / therapeutic use

Substances

  • Blood Proteins
  • Copper
  • Creatinine
  • Ceruloplasmin
  • Aspartate Aminotransferases
  • Alkaline Phosphatase
  • Trientine