Association of aspirin use with vitamin B12 deficiency (results of the BACH study)

Am J Cardiol. 2004 Oct 1;94(7):975-7. doi: 10.1016/j.amjcard.2004.06.047.

Abstract

We examined the prevalence of vitamin B(12) deficiency and its association with medication use and characteristics, including infection with Helicobacter pylori (H. pylori), in 255 patients hospitalized for cardiovascular disease. In almost half of the study population, vitamin B(12) deficiency was found; patients using acetylsalicylic acid were more frequently vitamin B(12) deficient in comparison to nonusers (p = 0.02). Fifty-one percent of the patients were infected with H. pylori, and fewer infected patients were vitamin B(12) deficient.

Publication types

  • Comparative Study
  • Evaluation Study

MeSH terms

  • Age Factors
  • Aged
  • Anti-Inflammatory Agents, Non-Steroidal / adverse effects
  • Anti-Inflammatory Agents, Non-Steroidal / therapeutic use*
  • Antibodies, Viral / blood
  • Antibodies, Viral / drug effects
  • Aspirin / adverse effects
  • Aspirin / therapeutic use*
  • Biomarkers / blood
  • Cardiovascular Diseases / blood
  • Cardiovascular Diseases / drug therapy
  • Cardiovascular Diseases / epidemiology
  • Female
  • Helicobacter Infections / blood
  • Helicobacter Infections / chemically induced*
  • Helicobacter Infections / epidemiology
  • Humans
  • Male
  • Middle Aged
  • Netherlands / epidemiology
  • Platelet Aggregation Inhibitors / adverse effects
  • Platelet Aggregation Inhibitors / therapeutic use*
  • Prevalence
  • Statistics as Topic
  • Treatment Outcome
  • Vitamin B 12 / blood
  • Vitamin B 12 Deficiency / blood
  • Vitamin B 12 Deficiency / chemically induced*
  • Vitamin B 12 Deficiency / epidemiology

Substances

  • Anti-Inflammatory Agents, Non-Steroidal
  • Antibodies, Viral
  • Biomarkers
  • Platelet Aggregation Inhibitors
  • Vitamin B 12
  • Aspirin