Caveolae meet endosomes: a stable relationship?

Dev Cell. 2004 Oct;7(4):458-60. doi: 10.1016/j.devcel.2004.09.009.

Abstract

The endocytic trafficking of caveolae has been the subject of some controversy for many years. A new study (Pelkmans et al.) shows that budded caveolae can interact with both the caveosome and the early endosome and that caveolin-enriched regions of the early endosomal membrane form unusually stable domains that can incorporate cargo in a regulated manner.

Publication types

  • Comparative Study

MeSH terms

  • Caveolae / metabolism*
  • Endocytosis
  • Endosomes / chemistry
  • Endosomes / metabolism*
  • Models, Biological
  • Protein Structure, Tertiary