Abstract
Whole-genome sequences are now available, and methods have evolved for targeting, in parallel, each gene in a genome, offering for the first time the opportunity to study the entire dynamic network of genes involved in aging. At a recent conference in Hersonissos, Crete, around 200 internationally renowned experts gathered to discuss techniques and emerging results as the science of aging undergoes a shift toward systems biology.
MeSH terms
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Aging / genetics
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Aging / pathology
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Alzheimer Disease / genetics
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Alzheimer Disease / pathology
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Animals
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Caenorhabditis elegans / genetics
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Caenorhabditis elegans Proteins / physiology
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Computational Biology / methods*
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Computational Biology / trends*
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Drosophila / genetics
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Drosophila Proteins / physiology
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Forkhead Transcription Factors
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Genes / physiology*
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Humans
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Immediate-Early Proteins
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Insulin / physiology
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Insulin-Like Growth Factor I / physiology
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Longevity / physiology*
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Mice
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Nuclear Proteins / physiology
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Protein Serine-Threonine Kinases / physiology
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Receptor, Insulin / physiology
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Signal Transduction / physiology
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Transcription Factors / physiology
Substances
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Caenorhabditis elegans Proteins
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Drosophila Proteins
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Forkhead Transcription Factors
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Immediate-Early Proteins
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Insulin
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Nuclear Proteins
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Transcription Factors
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daf-16 protein, C elegans
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Insulin-Like Growth Factor I
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DAF-2 protein, C elegans
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Receptor, Insulin
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Protein Serine-Threonine Kinases
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serum-glucocorticoid regulated kinase