Successful treatment of relapsing polychondritis with infliximab

C Richez; C Dumoulin; X Coutouly; T Schaeverbeke

Successful treatment of relapsing polychondritis with infliximab

Clin Exp Rheumatol. 2004 Sep-Oct;22(5):629-31.

Authors

C Richez¹, C Dumoulin, X Coutouly, T Schaeverbeke

Affiliation

¹ Service de Rhumatologie, Groupe Hospitalier Pellegrin, CHU de Bordeaux, Bordeaux, France. [email protected]

PMID: 15485019

Abstract

Relapsing polychondritis (RP) is a rare and potentially fatal autoimmune disease in which an inappropriate immune response destroys the cartilage of the ears, larynx and nose. Many therapeutic approaches have been reported. We describe the results obtained with infliximab in a patient with RP unresponsive to conventional therapy. This therapy could be a new weapon to treat refractory RP.

Publication types

Case Reports

MeSH terms

Adult
Antibodies, Monoclonal / immunology
Antibodies, Monoclonal / therapeutic use*
Antirheumatic Agents / immunology
Antirheumatic Agents / therapeutic use*
Humans
Infliximab
Male
Polychondritis, Relapsing / drug therapy*
Polychondritis, Relapsing / immunology
Treatment Outcome
Tumor Necrosis Factor-alpha / immunology*

Substances

Antibodies, Monoclonal
Antirheumatic Agents
Tumor Necrosis Factor-alpha
Infliximab