Gastric duplication in an adult mimicking mucinous cystadenoma of the pancreas

J Clin Pathol. 2004 Nov;57(11):1215-8. doi: 10.1136/jcp.2004.019091.

Abstract

Gastric duplication cyst (GDC) in an adult can have several clinical presentations. A review of the literature showed previously reported cases of GDC presenting as pancreatic pseudocyst or with greatly raised concentrations of carbohydrate antigen 19-9 (CA 19-9). It is often difficult to discriminate GDC from pancreatic cystic tumour, in particular pancreatic mucinous cystadenoma, in which concentrations of carcinoembryonic antigen and CA 19-9 are classically raised. This report describes an adult case of GDC mimicking a mucinous cystadenoma of the pancreas. This is the first report of a simultaneous increase in carcinoembryonic antigen and CA 19-9 in GDC in the absence of malignancy. Although few cases of carcinoma arising from a GDC having been reported, the production of oncofetal antigens raises the problem of a precancerous condition in long standing intestinal duplications. In this situation surgical resection must be performed.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Cystadenoma, Mucinous / diagnosis*
  • Cysts / congenital
  • Cysts / diagnosis*
  • Cysts / pathology
  • Diagnosis, Differential
  • Epithelium / pathology
  • Female
  • Humans
  • Pancreatic Neoplasms / diagnosis*
  • Stomach / abnormalities*
  • Stomach Diseases / congenital
  • Stomach Diseases / diagnosis*
  • Stomach Diseases / pathology
  • Tomography, X-Ray Computed