Abstract
We have found CueO from Escherichia coli to have a robust cuprous oxidase activity, severalfold higher than any homologue. These data suggest that a functional role for CueO in protecting against copper toxicity in vivo includes the removal of Cu(I).
Publication types
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Research Support, U.S. Gov't, Non-P.H.S.
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Copper / metabolism
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Copper / toxicity*
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Escherichia coli / drug effects
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Escherichia coli / enzymology*
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Escherichia coli Proteins / genetics
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Escherichia coli Proteins / metabolism
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Oxidoreductases / genetics
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Oxidoreductases / metabolism*
Substances
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Escherichia coli Proteins
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Copper
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Oxidoreductases
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cueO protein, E coli
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copper oxidase