Micromotor endoscope catheter for in vivo, ultrahigh-resolution optical coherence tomography

Opt Lett. 2004 Oct 1;29(19):2261-3. doi: 10.1364/ol.29.002261.

Abstract

A distally actuated, rotational-scanning micromotor endoscope catheter probe is demonstrated for ultrahigh-resolution in vivo endoscopic optical coherence tomography (OCT) imaging. The probe permits focus adjustment for visualization of tissue morphology at varying depths with improved transverse resolution compared with standard OCT imaging probes. The distal actuation avoids nonuniform scanning motion artifacts that are present with other probe designs and can permit a wider range of imaging speeds. Ultrahigh-resolution endoscopic imaging is demonstrated in a rabbit with <4-microm axial resolution by use of a femtosecond Cr:forsterite laser light source. The micromotor endoscope catheter probe promises to improve OCT imaging performance in future endoscopic imaging applications.

Publication types

  • Evaluation Study
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Catheterization / instrumentation*
  • Catheterization / methods
  • Colon / cytology*
  • Colonoscopes
  • Colonoscopy / methods
  • Endoscopes*
  • Endoscopy / methods
  • Equipment Design
  • Equipment Failure Analysis
  • Image Enhancement / instrumentation*
  • Miniaturization / methods
  • Motion
  • Rats
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Tomography, Optical Coherence / instrumentation*
  • Tomography, Optical Coherence / methods