Abstract
The opportunistic pathogen Pseudomonas aeruginosa causes both acute and chronic airway infections. In a recent issue of Developmental Cell, Goodman et al. (2004) show that the RetS two-component gene regulatory module inversely controls expression of genes associated with acute and chronic infection.
MeSH terms
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Acute Disease
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Chronic Disease
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Gene Expression Profiling
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Gene Expression Regulation, Bacterial
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Genes, Bacterial
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Genes, Regulator
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Mutation
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Pseudomonas Infections / genetics*
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Pseudomonas Infections / microbiology
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Pseudomonas aeruginosa / genetics*
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Pseudomonas aeruginosa / pathogenicity*
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Signal Transduction