Memory complaints in nondemented men predict future pathologic diagnosis of Alzheimer disease

Neurology. 2004 Nov 23;63(10):1960-1. doi: 10.1212/01.wnl.0000144348.70643.f2.

Abstract

The validity of memory complaints as a predictor of Alzheimer disease (AD) was assessed in 237 Japanese-American men autopsied at ages 74 to 97 years. These men were free of dementia at the time memory complaints were assessed 1 to 11 years earlier. Memory complaints were found to predict the neuropathologic diagnosis of AD after adjusting for age, time to death, education, depression, and cognitive functioning.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Alzheimer Disease / diagnosis
  • Alzheimer Disease / epidemiology*
  • Appointments and Schedules
  • Asian
  • Cohort Studies
  • Depression / epidemiology
  • Disease Progression
  • Educational Status
  • Face
  • Follow-Up Studies
  • Hawaii / epidemiology
  • Humans
  • Logistic Models
  • Male
  • Memory Disorders / epidemiology*
  • Names
  • Odds Ratio
  • Prospective Studies
  • Psychological Tests
  • Risk Factors