Abstract
The authors report the longitudinal case study of a patient with the right temporal variant of frontotemporal lobar degeneration. His deficit, initially limited to visuoperceptual disturbances, progressed 2 years later to a severe semantic breakdown. Neuroimaging data indicate that the underlying degenerative process, initially confined to unimodal visual associative cortices, progressed along the ventral pathways to multimodal areas in charge of integrating knowledge from various modalities (the anterior temporal lobes).
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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Aged
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Atrophy
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Cerebral Cortex / pathology*
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Disease Progression
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Family
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Famous Persons
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Follow-Up Studies
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Humans
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Imaging, Three-Dimensional
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Magnetic Resonance Imaging
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Male
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Memory Disorders / complications
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Memory Disorders / diagnostic imaging
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Memory Disorders / pathology
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Memory Disorders / psychology
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Neuropsychological Tests
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Prosopagnosia / complications
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Prosopagnosia / diagnostic imaging
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Prosopagnosia / pathology*
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Prosopagnosia / psychology
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Temporal Lobe / pathology
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Tomography, Emission-Computed, Single-Photon