Lymphoplasmacyte rich meningioma. A case report and review of the literature

J Neurosurg Sci. 2004 Sep;48(3):117-24; discussion 124.

Abstract

A peculiar type of meningioma with conspicious plasma-cell components is described. In accordance with the World Health Organization's Histological Typing of Tumours of the Central Nervous System, this rare clinical entity is recently designed as lymphoplasmacyte rich (LPR) meningioma. This type of meningioma is usually accompanied by prominent peripheral blood abnormalities, anemia and/or policlonal gammophaty, that disappear after surgical removal of the tumor. Actually, the origin (neoplastic or inflammatory) of this tumor is unclear; its biological behavior and clinical course are anomalous so it is considered closer to intracranial inflammatory masses rather than typical meningioma. In this paper, a new case of intracranial LPR meningioma occurring in a woman, is reported and a review the literature is made.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Anemia / complications*
  • Anemia / diagnosis
  • B-Lymphocytes / immunology
  • B-Lymphocytes / metabolism
  • B-Lymphocytes / pathology
  • Biomarkers, Tumor / biosynthesis
  • Craniotomy
  • Dizziness / etiology
  • Female
  • Headache / etiology
  • Humans
  • Magnetic Resonance Imaging
  • Meningeal Neoplasms / complications
  • Meningeal Neoplasms / pathology*
  • Meningeal Neoplasms / surgery
  • Meningioma / complications
  • Meningioma / pathology*
  • Meningioma / surgery
  • Middle Aged
  • Neoplasm, Residual / diagnosis*
  • Plasma Cells / pathology*
  • Treatment Outcome

Substances

  • Biomarkers, Tumor